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Identification of functionally connected multi-omic biomarkers for Alzheimer’s disease using modularity-constrained Lasso
Large-scale genome wide association studies (GWASs) have led to discovery of many genetic risk factors in Alzheimer’s disease (AD), such as APOE, TOMM40 and CLU. Despite the significant progress, it remains a major challenge to functionally validate these genetic findings and translate them into tar...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7299377/ https://ncbi.nlm.nih.gov/pubmed/32555747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234748 |
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