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Progress in Polygenic Composite Scores in Alzheimer’s and other Complex Diseases

Advances in high-throughput genotyping and next generation sequencing coupled with larger sample sizes brings the realization of precision medicine closer than ever. Polygenic approaches incorporating the aggregate influence of multiple genetic variants can contribute to a better understanding of th...

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Detalhes bibliográficos
Publicado no:Trends Genet
Main Authors: Chasioti, Danai, Yan, Jingwen, Nho, Kwangsik, Saykin, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475476/
https://ncbi.nlm.nih.gov/pubmed/30922659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.02.005
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