Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner

Renal dysplasia, the major cause of childhood renal failure, is characterized by defective branching morphogenesis and nephrogenesis. Beta-catenin, a transcription factor and cell adhesion molecule, is markedly increased in the nucleus of kidney cells in human renal dysplasia and contributes to its...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Cunanan, Joanna, Deacon, Erin, Cunanan, Kristina, Yang, Zifan, Ask, Antje, Morikawa, Lily, Todorova, Ekaterina, Bridgewater, Darren
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299361/
https://ncbi.nlm.nih.gov/pubmed/32555682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234375
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