Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.

In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of beta-catenin, which then associates with the lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) to activate target genes. Wnt/beta -catenin signalling is essential for T cell developme...

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Hlavní autoři:	Dimple Notani, Kamalvishnu P Gottimukkala, Ranveer S Jayani, Amita S Limaye, Madhujit V Damle, Sameet Mehta, Prabhat Kumar Purbey, Jomon Joseph, Sanjeev Galande
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2010-01-01
Edice:	PLoS Biology
On-line přístup:	https://doi.org/10.1371/journal.pbio.1000296
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