Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

Mitochondrial membrane dynamics is a cellular rheostat that relates metabolic function and organelle morphology. Using an in vitro reconstitution system, we describe a mechanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two forms of Opa1. We found that the long-form of...

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Vydáno v:eLife
Hlavní autoři: Ge, Yifan, Shi, Xiaojun, Boopathy, Sivakumar, McDonald, Julie, Smith, Adam W, Chao, Luke H
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Structural Biology and Molecular Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299343/
https://ncbi.nlm.nih.gov/pubmed/31922487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50973
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