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Role of inner mitochondrial protein OPA1 in mitochondrial dysfunction by tobacco smoking and in the pathogenesis of COPD

BACKGROUND: Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are linked to several mitochondrial alterations. Cigarette smoke (CS) alters the structure and function of mitochondria. OPA1 is the main inner mitochondrial GTPase respons...

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Publicat a:Redox Biol
Autors principals: Maremanda, Krishna Prahlad, Sundar, Isaac Kirubakaran, Rahman, Irfan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258692/
https://ncbi.nlm.nih.gov/pubmed/34214709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102055
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