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Role of the central junction in folding topology of the protein-free human U2–U6 snRNA complex

U2 and U6 small nuclear (sn)RNAs are the only snRNAs directly implicated in catalyzing the splicing of pre-mRNA, but assembly and rearrangement steps prior to catalysis require numerous proteins. Previous studies have shown that the protein-free U2–U6 snRNA complex adopts two conformations in equili...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA
Egile Nagusiak: Chu, Huong, Perea, William, Greenbaum, Nancy L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297123/
https://ncbi.nlm.nih.gov/pubmed/32220895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073379.119
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