β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes

BACKGROUND: The Wnt/β-catenin signaling pathway is a prolific regulator of cell-to-cell communication and gene expression. Canonical Wnt/β-catenin signaling involves partnering of β-catenin with members of the TCF/LEF family of transcription factors (TCF1, TCF3, TCF4, LEF1) to regulate gene expressi...

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Publicado en:Cell Commun Signal
Autores principales: Robinson, KaReisha F., Narasipura, Srinivas D., Wallace, Jennillee, Ritz, Ethan M., Al-Harthi, Lena
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296971/
https://ncbi.nlm.nih.gov/pubmed/32546183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00565-2
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