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Negative regulation of IL-8 in human astrocytes depends on β-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction

Expression of cytokines/chemokines is tightly regulated at the transcription level. This is crucial in the central nervous system to maintain neuroimmune homeostasis. IL-8 a chemoattractant, which recruits neutrophils, T cells, and basophils into the brain in response to inflammation and/or injury i...

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Bibliografiske detaljer
Udgivet i:Cytokine
Main Authors: Robinson, KaReisha F., Narasipura, Srinivas D., Wallace, Jennillee, Ritz, Ethan M., Al-Harthi, Lena
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554258/
https://ncbi.nlm.nih.gov/pubmed/32818703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2020.155252
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