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Evolution Conserves the Network of Coupled Residues in Dihydrofolate Reductase

Understanding protein motions and their role in enzymatic reactions is an important and timely topic in enzymology. Protein motions that are involved in the chemical step of catalysis are particularly intriguing but difficult to identify. A global network of coupled residues in Escherichia coli dihy...

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Publicado en:Biochemistry
Autores principales: Li, Jiayue, Fortunato, Gabriel, Lin, Jennifer, Agarwal, Pratul K., Kohen, Amnon, Singh, Priyanka, Cheatum, Christopher M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296831/
https://ncbi.nlm.nih.gov/pubmed/31423766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00460
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