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Insights into structural and dynamical changes experienced by human RNase 6 upon ligand binding

Ribonuclease 6 (RNase 6) is one of eight catalytically active human pancreatic-type RNases that belong to a superfamily of rapidly evolving enzymes. Like some of its human homologs, RNase 6 exhibits host defense properties such as antiviral and antibacterial activities. Recently solved crystal struc...

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Bibliografiska uppgifter
I publikationen:Biochemistry
Huvudupphovsmän: Narayanan, Chitra, Bernard, David N., Létourneau, Myriam, Gagnon, Jacinthe, Gagné, Donald, Bafna, Khushboo, Calmettes, Charles, Couture, Jean-François, Agarwal, Pratul K., Doucet, Nicolas
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296828/
https://ncbi.nlm.nih.gov/pubmed/31909602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00888
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