Non-sterilizing, Infection-Permissive Vaccination With Inactivated Influenza Virus Vaccine Reshapes Subsequent Virus Infection-Induced Protective Heterosubtypic Immunity From Cellular to Humoral Cross-Reactive Immune Responses

Conventional influenza vaccines aim at the induction of virus-neutralizing antibodies that provide with sterilizing immunity. However, influenza vaccination often confers protection from disease but not from infection. The impact of infection-permissive vaccination on the immune response elicited by...

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Udgivet i:Front Immunol
Main Authors: Choi, Angela, Ibañez, Lorena I., Strohmeier, Shirin, Krammer, Florian, García-Sastre, Adolfo, Schotsaert, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296151/
https://ncbi.nlm.nih.gov/pubmed/32582220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01166
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