Roseotoxin B alleviates cholestatic liver fibrosis through inhibiting PDGF-B/PDGFR-β pathway in hepatic stellate cells

Identifying effective anti-fibrotic therapies is a major clinical need that remains unmet. In the present study, roseotoxin B was shown to possess an improving effect on cholestatic liver fibrosis in bile duct–ligated mice, as proved by histochemical and immunohistochemical staining, hepatic biochem...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Xingqi, Gao, Yuzhi, Li, Yu, Huang, Yuqing, Zhu, Yawen, lv, Wei, Wang, Ruzeng, Gou, Lingshan, Cheng, Chao, Feng, Zhaojun, Xie, Jun, Tian, Jun, Yao, Ruiqin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296008/
https://ncbi.nlm.nih.gov/pubmed/32541811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2575-0
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