A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans ass...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H. M., Astrup, Arne, Hager, Jörg, Davison, Anthony C., Valsesia, Armand
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295243/
https://ncbi.nlm.nih.gov/pubmed/32492067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007882
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