Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Thousands of genetic variants have been associated with complex traits through genome-wide association studies. However, the functional variants or mechanistic consequences remain elusive. Intermediate traits such as gene expression or protein levels are good proxies of the metabolic state of an org...

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Publicado no:Nat Commun
Main Authors: Carayol, Jérôme, Chabert, Christian, Di Cara, Alessandro, Armenise, Claudia, Lefebvre, Gregory, Langin, Dominique, Viguerie, Nathalie, Metairon, Sylviane, Saris, Wim H. M., Astrup, Arne, Descombes, Patrick, Valsesia, Armand, Hager, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727191/
https://ncbi.nlm.nih.gov/pubmed/29234017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02182-z
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