A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans ass...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H. M., Astrup, Arne, Hager, Jörg, Davison, Anthony C., Valsesia, Armand
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295243/
https://ncbi.nlm.nih.gov/pubmed/32492067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007882
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