A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans ass...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H. M., Astrup, Arne, Hager, Jörg, Davison, Anthony C., Valsesia, Armand
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295243/
https://ncbi.nlm.nih.gov/pubmed/32492067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007882
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