Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Thousands of genetic variants have been associated with complex traits through genome-wide association studies. However, the functional variants or mechanistic consequences remain elusive. Intermediate traits such as gene expression or protein levels are good proxies of the metabolic state of an org...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Carayol, Jérôme, Chabert, Christian, Di Cara, Alessandro, Armenise, Claudia, Lefebvre, Gregory, Langin, Dominique, Viguerie, Nathalie, Metairon, Sylviane, Saris, Wim H. M., Astrup, Arne, Descombes, Patrick, Valsesia, Armand, Hager, Jörg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727191/
https://ncbi.nlm.nih.gov/pubmed/29234017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02182-z
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