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Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies

Neurotoxicity is an important and common complication of chimeric antigen receptor-T cell therapies. Acute neurologic signs and/or symptoms occur in a significant proportion of patients treated with CD19-directed chimeric antigen receptor-T cells for B-cell malignancies. Clinical manifestations incl...

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Detalhes bibliográficos
Publicado no:CNS Drugs
Main Authors: Gust, Juliane, Taraseviciute, Agne, Turtle, Cameron J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295115/
https://ncbi.nlm.nih.gov/pubmed/30387077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-018-0582-9
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