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Insights into cytokine release syndrome and neurotoxicity after CD19-specific CAR-T cell therapy
T-cells engineered to express CD19-specific chimeric antigen receptors (CD19 CAR-T cells) can achieve high response rates in patients with refractory/relapsed (R/R) CD19+ hematologic malignancies. Nonetheless, the efficacy of CD19-specific CAR-T cell therapy can be offset by significant toxicities,...
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| Veröffentlicht in: | Curr Res Transl Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5967886/ https://ncbi.nlm.nih.gov/pubmed/29625831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.retram.2018.03.003 |
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