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Chimeric Antigen Receptor (CAR) T cells: Lessons Learned from Targeting of CD19 in B cell malignancies

Adoptive immunotherapy with chimeric antigen receptor-modified T (CAR-T) cells is a rapidly growing therapeutic approach to treating patients with refractory cancer, with over 100 clinical trials in various malignancies in progress. The enthusiasm for CAR-T cells has been driven by the clinical succ...

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Detalhes bibliográficos
Publicado no:Drugs
Main Authors: Hay, Kevin A, Turtle, Cameron J
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603178/
https://ncbi.nlm.nih.gov/pubmed/28110394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-017-0690-8
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