CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Mature Primary Innate Immune Cells

CRISPR genome engineering has become a powerful tool to functionally investigate the complex mechanisms of immune system regulation. While decades of work have aimed to genetically reprogram innate immunity, the utility of current approaches is restricted by poor knockout efficiencies or limited spe...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Riggan, Luke, Hildreth, Andrew D., Rolot, Marion, Wong, Yung-Yu, Satyadi, William, Sun, Ryan, Huerta, Christopher, O’Sullivan, Timothy E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294876/
https://ncbi.nlm.nih.gov/pubmed/32433960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107651
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