Discovery of Novel Nonpeptidic PAR2 Ligands

[Image: see text] Proteinase-activated receptor 2 (PAR2) is a class A G protein-coupled receptor whose activation has been associated with inflammatory diseases and cancer, thus representing a valuable therapeutic target. Pathophysiological roles of PAR2 are often characterized using peptidic PAR2 a...

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Udgivet i:ACS Med Chem Lett
Main Authors: Klösel, Ilona, Schmidt, Maximilian F., Kaindl, Jonas, Hübner, Harald, Weikert, Dorothee, Gmeiner, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294704/
https://ncbi.nlm.nih.gov/pubmed/32551018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00154
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