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Functionally selective activation of the dopamine receptor D(2) is mirrored by the protein expression profiles
The development of functionally selective or biased ligands is a promising approach towards drugs with less side effects. Biased ligands for G protein-coupled receptors can selectively induce G protein activation or β-arrestin recruitment. The consequences of this selective action on cellular functi...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875989/ https://ncbi.nlm.nih.gov/pubmed/33568753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83038-x |
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