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Agonists of G‑Protein-Coupled Odorant Receptors Are Predicted from Chemical Features

Predicting the activity of chemicals for a given odorant receptor is a longstanding challenge. Here the activity of 258 chemicals on the human G-protein-coupled odorant receptor (OR)51E1, also known as prostate-specific G-protein-coupled receptor 2 (PSGR2), was virtually screened by machine learning...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Phys Chem Lett
Prif Awduron: Bushdid, C., de March, C. A., Fiorucci, S., Matsunami, H., Golebiowski, J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294703/
https://ncbi.nlm.nih.gov/pubmed/29648835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.8b00633
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