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Mammalian class I odorant receptors exhibit a conserved vestibular-binding pocket

Odorant receptors represent the largest family of mammalian G protein-coupled receptors. Phylogenetically, they are split into two classes (I and II). By analyzing the entire subclass I odorant receptors sequences, we identified two class I-specific and highly conserved motifs. These are predicted t...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Life Sci
Hauptverfasser: Bushdid, Caroline, de March, Claire A., Topin, Jérémie, Do, Matthew, Matsunami, Hiroaki, Golebiowski, Jérôme
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313674/
https://ncbi.nlm.nih.gov/pubmed/30599066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2996-4
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