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Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors
Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled receptors expressed in olfactory cilia membranes. Most odorant receptors show little to no cell surface expression in nonolfactory cells due to endoplasmic reticulum retention, which has slowed down biochemical s...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7022149/ https://ncbi.nlm.nih.gov/pubmed/31974307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915520117 |
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