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Responsiveness of G protein-coupled odorant receptors is partially attributed to the activation mechanism
Mammals detect and discriminate numerous odors via a large family of G protein-coupled odorant receptors (ORs). However, little is known about the molecular and structural basis underlying OR response properties. Using site-directed mutagenesis and computational modeling, we studied ORs sharing high...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672800/ https://ncbi.nlm.nih.gov/pubmed/26627247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517510112 |
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