Tumor characteristics associated with engraftment of patient-derived non-small cell lung cancer xenografts in immunocompromised mice

BACKGROUND: Patient-derived xenograft (PDX) models are increasingly used in translational research, however, the engraftment rates of patient tumor samples in immunodeficient mice to PDX models vary greatly. METHODS: Tumor tissue samples from 308 NSCLC patients were implanted in immunodeficient mice...

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Publicat a:Cancer
Autors principals: Chen, Yungchang, Zhang, Ran, Wang, Li, Correa, Arlene M., Pataer, Apar, Xu, Yi, Zhang, Xiaoshan, Ren, Chenghui, Wu, Shuhong, Meng, Qing H, Fujimoto, Junya, Jensen, Vanessa B., Antonoff, Mara B., Hofstetter, Wayne L., Mehran, Reza J., Pisimisis, George, Rice, David C., Sepesi, Boris, Vaporciyan, Ara A., Walsh, Garrett L., Swisher, Stephen G., Roth, Jack A., Heymach, John V., Fang, Bingliang
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294643/
https://ncbi.nlm.nih.gov/pubmed/31287557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32366
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