Tumor characteristics associated with engraftment of patient-derived non-small cell lung cancer xenografts in immunocompromised mice

BACKGROUND: Patient-derived xenograft (PDX) models are increasingly used in translational research, however, the engraftment rates of patient tumor samples in immunodeficient mice to PDX models vary greatly. METHODS: Tumor tissue samples from 308 NSCLC patients were implanted in immunodeficient mice...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Chen, Yungchang, Zhang, Ran, Wang, Li, Correa, Arlene M., Pataer, Apar, Xu, Yi, Zhang, Xiaoshan, Ren, Chenghui, Wu, Shuhong, Meng, Qing H, Fujimoto, Junya, Jensen, Vanessa B., Antonoff, Mara B., Hofstetter, Wayne L., Mehran, Reza J., Pisimisis, George, Rice, David C., Sepesi, Boris, Vaporciyan, Ara A., Walsh, Garrett L., Swisher, Stephen G., Roth, Jack A., Heymach, John V., Fang, Bingliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294643/
https://ncbi.nlm.nih.gov/pubmed/31287557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32366
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