Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

Molecular annotated patient-derived xenograft (PDX) models are useful for the preclinical investigation of anticancer drugs and individualized anticancer therapy. We established 23 PDXs from 88 surgical specimens of lung cancer patients and determined gene mutations in these PDXs and their paired pr...

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Vydáno v:Cancer Lett
Hlavní autoři: Hao, Chuncheng, Wang, Li, Peng, Shaohua, Cao, Mengru, Li, Hongyu, Hu, Jing, Huang, Xiao, Liu, Wei, Zhang, Hui, Wu, Shuhong, Pataer, Apar, Heymach, John V., Eterovic, Agda Karina, Zhang, Qingxiu, Shaw, Kenna R., Chen, Ken, Futreal, Andrew, Wang, Michael, Hofstetter, Wayne, Mehran, Reza, Rice, David, Roth, Jack A., Sepesi, Boris, Swisher, Stephen G., Vaporciyan, Ara, Walsh, Garrett L., Johnson, Faye M., Fang, Bingliang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301580/
https://ncbi.nlm.nih.gov/pubmed/25444907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.11.024
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