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Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

Molecular annotated patient-derived xenograft (PDX) models are useful for the preclinical investigation of anticancer drugs and individualized anticancer therapy. We established 23 PDXs from 88 surgical specimens of lung cancer patients and determined gene mutations in these PDXs and their paired pr...

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書誌詳細
出版年:Cancer Lett
主要な著者: Hao, Chuncheng, Wang, Li, Peng, Shaohua, Cao, Mengru, Li, Hongyu, Hu, Jing, Huang, Xiao, Liu, Wei, Zhang, Hui, Wu, Shuhong, Pataer, Apar, Heymach, John V., Eterovic, Agda Karina, Zhang, Qingxiu, Shaw, Kenna R., Chen, Ken, Futreal, Andrew, Wang, Michael, Hofstetter, Wayne, Mehran, Reza, Rice, David, Roth, Jack A., Sepesi, Boris, Swisher, Stephen G., Vaporciyan, Ara, Walsh, Garrett L., Johnson, Faye M., Fang, Bingliang
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301580/
https://ncbi.nlm.nih.gov/pubmed/25444907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.11.024
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