Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

Molecular annotated patient-derived xenograft (PDX) models are useful for the preclinical investigation of anticancer drugs and individualized anticancer therapy. We established 23 PDXs from 88 surgical specimens of lung cancer patients and determined gene mutations in these PDXs and their paired pr...

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Publicado en:Cancer Lett
Autores principales: Hao, Chuncheng, Wang, Li, Peng, Shaohua, Cao, Mengru, Li, Hongyu, Hu, Jing, Huang, Xiao, Liu, Wei, Zhang, Hui, Wu, Shuhong, Pataer, Apar, Heymach, John V., Eterovic, Agda Karina, Zhang, Qingxiu, Shaw, Kenna R., Chen, Ken, Futreal, Andrew, Wang, Michael, Hofstetter, Wayne, Mehran, Reza, Rice, David, Roth, Jack A., Sepesi, Boris, Swisher, Stephen G., Vaporciyan, Ara, Walsh, Garrett L., Johnson, Faye M., Fang, Bingliang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301580/
https://ncbi.nlm.nih.gov/pubmed/25444907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.11.024
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