Orexin A alleviates neuroinflammation via OXR2/CaMKKβ/AMPK signaling pathway after ICH in mice

BACKGROUND: Orexins are two neuropeptides (orexin A, OXA; orexin B, OXB) secreted mainly from the lateral hypothalamus, which exert a wide range of physiological effects by activating two types of receptors (orexin receptor 1, OXR1; orexin receptor 2, OXR2). OXA has equal affinity for OXR1 and OXR2,...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Li, Tao, Xu, Weilin, Ouyang, Jinsong, Lu, Xiaoyang, Sherchan, Prativa, Lenahan, Cameron, Irio, Giselle, Zhang, John H., Zhao, Jianhua, Zhang, Yongfa, Tang, Jiping
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294616/
https://ncbi.nlm.nih.gov/pubmed/32539736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01841-1
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