Chemerin suppresses neuroinflammation and improves neurological recovery via CaMKK2/AMPK/Nrf2 pathway after germinal matrix hemorrhage in neonatal rats

Chemerin, an adipokine, has been reported to reduce the production of pro-inflammatory cytokines and neutrophil infiltration. This study investigated the role of Chemerin and its natural receptor, ChemR23, as well as its downstream mediator calmodulin-dependent protein kinase kinase 2 (CAMKK2)/adeno...

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Vydáno v:Brain Behav Immun
Hlavní autoři: Zhang, Yixin, Xu, Ningbo, Ding, Yan, Zhang, Yiting, Li, Qian, Flores, Jerry, Haghighiabyaneh, Mina, Doycheva, Desislava, Tang, Jiping, Zhang, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953818/
https://ncbi.nlm.nih.gov/pubmed/29499303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2018.02.015
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