CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

BACKGROUND: Endothelial dysfunction and apoptosis resulting from oxidative stress can lead to the development of atherosclerosis. Our group has previously showed that CD137 signaling contributes to the progression of atherosclerosis and the vulnerability of plaques. The aim of this study is to inves...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mediators Inflamm
Auteurs principaux: Geng, Tianxin, Yan, Yang, Zhang, Yue, Xu, Liangjie, Zang, Guangyao, Yan, Jin Chuan
Format: Artigo
Langue:Inglês
Publié: Hindawi 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294359/
https://ncbi.nlm.nih.gov/pubmed/32587470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4321912
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