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CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

BACKGROUND: Endothelial dysfunction and apoptosis resulting from oxidative stress can lead to the development of atherosclerosis. Our group has previously showed that CD137 signaling contributes to the progression of atherosclerosis and the vulnerability of plaques. The aim of this study is to inves...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Geng, Tianxin, Yan, Yang, Zhang, Yue, Xu, Liangjie, Zang, Guangyao, Yan, Jin Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294359/
https://ncbi.nlm.nih.gov/pubmed/32587470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4321912
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