Pristimerin‐induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway

Uveal melanoma (UM) is a highly invasive intraocular malignancy with high mortality. Presently, there is no FDA‐approved standard for the treatment of metastatic UM. Pristimerin is a natural quinine methide triterpenoid compound with anti‐angiogenic, anti‐cancer and anti‐inflammatory activities. How...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yan, Fengxia, Liao, Rifang, Silva, Marta, Li, Shuai, Jiang, Yizhou, Peng, Tangming, Lazarovici, Philip, Zheng, Wenhua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294164/
https://ncbi.nlm.nih.gov/pubmed/32347651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15249
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