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Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects
The transcription factor RUNX1, a pivotal regulator of HSCs and haematopoiesis, is a frequent target of chromosomal translocations, point mutations or altered gene/protein dosage. These modifications lead or contribute to the development of myelodysplasia, leukaemia or platelet disorders. A better u...
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| 出版年: | J Cell Mol Med |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7294146/ https://ncbi.nlm.nih.gov/pubmed/32323916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15269 |
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