Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects

The transcription factor RUNX1, a pivotal regulator of HSCs and haematopoiesis, is a frequent target of chromosomal translocations, point mutations or altered gene/protein dosage. These modifications lead or contribute to the development of myelodysplasia, leukaemia or platelet disorders. A better u...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Mol Med
Päätekijät: Mazzola, Mara, Pezzotta, Alex, Fazio, Grazia, Rigamonti, Alessandra, Bresciani, Erica, Gaudenzi, Germano, Pelleri, Maria Chiara, Saitta, Claudia, Ferrari, Luca, Parma, Matteo, Fumagalli, Monica, Biondi, Andrea, Cazzaniga, Giovanni, Marozzi, Anna, Pistocchi, Anna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294146/
https://ncbi.nlm.nih.gov/pubmed/32323916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15269
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