Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells

Viral immune evasion is currently understood to focus on deflecting CD8 T cell recognition of infected cells by disrupting antigen presentation pathways. We evaluated viral interference with the ultimate step in cytotoxic T cell function, the death of infected cells. The viral inhibitor of caspase-8...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Chaudhry, M. Zeeshan, Casalegno-Garduno, Rosaely, Sitnik, Katarzyna M., Kasmapour, Bahram, Pulm, Ann-Kathrin, Brizic, Ilija, Eiz-Vesper, Britta, Moosmann, Andreas, Jonjic, Stipan, Mocarski, Edward S., Cicin-Sain, Luka
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293702/
https://ncbi.nlm.nih.gov/pubmed/32444487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914667117
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