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Neuron-restricted cytomegalovirus latency in the central nervous system regulated by CD4+ T-cells and IFN-γ

Abstract All human herpesviruses establish latency following the resolution of the primary infection. Among these, α-herpesviruses HSV-1, HSV-2 and VZV establish latency in neurons, whereas neurons are not traditionally considered a site of latency for other herpesviruses. Using a combination of in...

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Kaydedildi:
Asıl Yazarlar: Fran Krstanović, Andrea Mihalić, Ahmad Seyar Rashidi, Katarzyna M. Sitnik, Zsolt Ruzsics, Luka Čičin-Šain, Georges M. G. M. Verjans, Stipan Jonjić, Ilija Brizić
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2025-03-01
Seri Bilgileri:Journal of Neuroinflammation
Konular:
Cytomegalovirus
Congenital CMV
Viral latency
Neurons
CD4+ T-cells
Hippocampus
Online Erişim:https://doi.org/10.1186/s12974-025-03422-6
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