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Selective Modification of Tryptophan Residues in Peptides and Proteins Using a Biomimetic Electron Transfer Process
We report here a photochemical process for the selective modification of tryptophan (Trp) residues in peptides and small proteins using electron-responsive N-carbamoylpyridinium salts and UV–B light. Preliminary mechanistic experiments suggest that the photoconjugation process proceeds through photo...
Gardado en:
| Publicado en: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7292481/ https://ncbi.nlm.nih.gov/pubmed/32348670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c03039 |
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