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Selective Modification of Tryptophan Residues in Peptides and Proteins Using a Biomimetic Electron Transfer Process

We report here a photochemical process for the selective modification of tryptophan (Trp) residues in peptides and small proteins using electron-responsive N-carbamoylpyridinium salts and UV–B light. Preliminary mechanistic experiments suggest that the photoconjugation process proceeds through photo...

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Publicado en:J Am Chem Soc
Autores principales: Tower, Samantha J., Hetcher, Wesley J., Myers, Tyler E., Kuehl, Nicholas J., Taylor, Michael T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292481/
https://ncbi.nlm.nih.gov/pubmed/32348670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c03039
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