Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

Background: MiR-146a is an important regulator of innate inflammatory responses and is also implicated in cell death and survival. Methods: By sorting CNS resident cells, microglia were the main cellular source of miR-146a. Therefore, we investigated microglia function and phenotype in miR-146a knoc...

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Vydáno v:Front Immunol
Hlavní autoři: Martin, Nellie A., Hyrlov, Kirsten H., Elkjaer, Maria L., Thygesen, Eva K., Wlodarczyk, Agnieszka, Elbaek, Kirstine J., Aboo, Christopher, Okarmus, Justyna, Benedikz, Eirikur, Reynolds, Richard, Hegedus, Zoltan, Stensballe, Allan, Svenningsen, Åsa Fex, Owens, Trevor, Illes, Zsolt
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292149/
https://ncbi.nlm.nih.gov/pubmed/32582192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01110
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