Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

Background: MiR-146a is an important regulator of innate inflammatory responses and is also implicated in cell death and survival. Methods: By sorting CNS resident cells, microglia were the main cellular source of miR-146a. Therefore, we investigated microglia function and phenotype in miR-146a knoc...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Martin, Nellie A., Hyrlov, Kirsten H., Elkjaer, Maria L., Thygesen, Eva K., Wlodarczyk, Agnieszka, Elbaek, Kirstine J., Aboo, Christopher, Okarmus, Justyna, Benedikz, Eirikur, Reynolds, Richard, Hegedus, Zoltan, Stensballe, Allan, Svenningsen, Åsa Fex, Owens, Trevor, Illes, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292149/
https://ncbi.nlm.nih.gov/pubmed/32582192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01110
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