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A decade of advances in transposon-insertion sequencing

It has been 10 years since the introduction of modern transposon-insertion sequencing (TIS) methods, which combine genome-wide transposon mutagenesis with high-throughput sequencing to estimate the fitness contribution or essentiality of each genetic component in a bacterial genome. Four TIS variati...

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Bibliografske podrobnosti
izdano v:Nat Rev Genet
Main Authors: Cain, Amy K., Barquist, Lars, Goodman, Andrew L., Paulsen, Ian T., Parkhill, Julian, van Opijnen, Tim
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291929/
https://ncbi.nlm.nih.gov/pubmed/32533119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-020-0244-x
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