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Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy

Shiga toxin (STx) produced by Shigella and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing Escherichia coli (STEC) are bacterial AB(5) toxins. All three toxins target kidney cells and may cause life-threatening renal disease. While Shigella infections can be...

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Foilsithe in:Toxins (Basel)
Main Authors: Li, Danyang, Selyunin, Andrey, Mukhopadhyay, Somshuvra
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290323/
https://ncbi.nlm.nih.gov/pubmed/32456007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12050342
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