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Functional analyses of the UDP-galactose transporter SLC35A2 using the binding of bacterial Shiga toxins as a novel activity assay

SLC35A2 transports UDP-galactose from the cytosol to the lumen of the Golgi apparatus and endoplasmic reticulum for glycosylation. Mutations in SLC35A2 induce a congenital disorder of glycosylation. Despite the biomedical relevance, mechanisms of transport via SLC35A2 and the impact of disease-assoc...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Li, Danyang, Mukhopadhyay, Somshuvra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521944/
https://ncbi.nlm.nih.gov/pubmed/30834435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz016
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