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A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1

HIV-1 infection is a complex, multi-step process involving not only viral, but also multiple cellular factors. To date, drug discovery methods have primarily focused on the inhibition of single viral proteins. We present an efficient and unbiased approach, compatible with biosafety level 1 (BSL-1) c...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Ellinger, Bernhard, Pohlmann, Daniel, Woens, Jannis, Jäkel, Felix M., Reinshagen, Jeanette, Stocking, Carol, Prassolov, Vladimir S., Fehse, Boris, Riecken, Kristoffer
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290285/
https://ncbi.nlm.nih.gov/pubmed/32466195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12050580
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