A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses

BACKGROUND: Despite progress in the development of combined antiretroviral therapies (cART), HIV infection remains a significant challenge for human health. Current problems of cART include multi-drug-resistant virus variants, long-term toxicity and enormous treatment costs. Therefore, the identific...

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Bibliographic Details
Main Authors: Prokofjeva, Maria M, Riecken, Kristoffer, Spirin, Pavel V, Yanvarév, Dimitriy V, Düsedau, Arne, Ellinger, Bernhard, Fehse, Boris, Stocking, Carol, Prassolov, Vladimir S
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560153/
https://ncbi.nlm.nih.gov/pubmed/23286882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-10-1
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