Načítá se...
Two-step mechanism of J-domain action in driving Hsp70 function
J-domain proteins (JDPs), obligatory Hsp70 cochaperones, play critical roles in protein homeostasis. They promote key allosteric transitions that stabilize Hsp70 interaction with substrate polypeptides upon hydrolysis of its bound ATP. Although a recent crystal structure revealed the physical mode o...
Uloženo v:
| Vydáno v: | PLoS Comput Biol |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2020
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289447/ https://ncbi.nlm.nih.gov/pubmed/32479549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007913 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|