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The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias
Polyglutamine (polyQ) spinocerebellar ataxias (SCAs) are the most prevalent subset of SCAs and share the aberrant expansion of Q-encoding CAG repeats within the coding sequences of disease-responsible genes as their common genetic cause. These polyQ SCAs (SCA1, SCA2, SCA3, SCA6, SCA7, and SCA17) are...
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| Yayımlandı: | Front Neurosci |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289180/ https://ncbi.nlm.nih.gov/pubmed/32581673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00489 |
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