Regulated proteolysis of MutSγ controls meiotic crossing over

Crossover recombination is essential for accurate chromosome segregation during meiosis. The MutSγ-complex, Msh4-Msh5, facilitates crossing over by binding and stabilizing nascent recombination intermediates. We show that these activities are governed by regulated proteolysis. MutSγ is initially ina...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: He, Wei, Rao, H.B.D. Prasada, Tang, Shangming, Bhagwat, Nikhil, Kulkarni, Dhananjaya S., Ma, Yunmei, Chang, Maria A.W., Hall, Christie, Wang-Bragg, Junxi, Manasca, Harrison S., Baker, Christa, Verhees, Gerrik F., Ranjha, Lepakshi, Chen, Xiangyu, Hollingsworth, Nancy M., Cejka, Petr, Hunter, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289160/
https://ncbi.nlm.nih.gov/pubmed/32130890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.02.001
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